| dc.description.abstract | Parkinson's disease (PD) is a neurological disease
caused by loss of activity of dopaminergic neurons
in substantia nigra and is characterized by presence
of lewy bodies in midbrain, Symptoms exhibited as
rest tremors, rigidity, bradykinesia, and posture
instability. The non motor symptoms include
constipation and REM sleep disorder (1,2)
.
Age is the biggest risk factor, and usually older
adults are affected, It is a multifactorial disease with
many environmental factors such as head injury
well water consumption, and pesticide exposure and
genetic mutations. The most important genes will be
discussed in the following sections | en_US |
