Fluoride Treatment and Risk of Fracture In Osteoporosis Patients

Osteoporosis is common systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to enhanced bone fragility and a consequent increase in fracture risk” • More common in postmenopausal Sodium fluoride stimulates bone formation and increases cancellous-bone mass Sodium fluoride (NaF) was currently the only pharmacological agent capable of stimulating bone formation through a direct effect on the osteoblast