Citric Acid Cycle

The citric acid cycle is the final pathway for the oxidation of carbohydrate, lipid, and protein whose common end-metabolite is acetyl-CoA. • The cycle is the major route for the generation of ATP and is located in the matrix of mitochondria. • Each turn of the cycle forms one GTP or ATP as well as three NADH molecules and one FADH2 molecule, which will be used in further steps of cellular respiration to produce ATP for the cell.