RELATION BETWEEN BRONCHITIS AND IMMUNOGLOBULIN
Severe bronchiolitis is a lower respiratory tract infectious disease, a common clinical acute and critical case in pediatrics, and the leading cause of death among children, and it is more common in children less than 2 y old. The main symptoms are recurrent wheezing, difficulty breathing, thus causing hypoxia, endothelial damage, and platelet activation leading to a hypercoagulable state..
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The goal of the present study is to explore the physiological effects of injected human immunoglobulin on patients with severe bronchiolitis before and after treatment. 86 young children with severe bronchiolitis were randomly divided into the observation group (43 cases) and the treatment group (43 cases). On the basis of conventional therapy, the children in the treatment group were given human immunoglobulin (400 mg/kg, 1–3 times) via intravenous injection. 60 healthy young children, as determined by a physical examination given at the Zhumadian Central Hospital, were enrolled as the control group. The T lymphocytes, cytokines, IgA, IgG, and IgM immunoglobulins in the peripheral blood of all 3 groups were measured. The clinical efficacy of the immunoglobulins to mitigate the effects of bronchiolitis and the amount of time for the reduction of symptoms to occur were observed
