Dental Features of William Syndrome

Williams syndrome is a multisystemic rare genetic disorder that was first described in 1961, by a cardiologist from New Zealand. Williams syndrome is caused by a deletion of 26–28 genes in the long arm of chromosome 7 at 7q11.23. The deletion occurs at the time of conception. It is characterized by a number of developmental and physical abnormalities including congenital cardiovascular abnormalities, mental retardation, neurological features, growth deficiency, genitourinary manifestations, gastrointestinal problems, musculoskeletal problems, unique behavioral characteristics, and dental problems