dc.contributor.author | salah, Abdulraof | |
dc.date.accessioned | 2019-04-20T10:38:31Z | |
dc.date.available | 2019-04-20T10:38:31Z | |
dc.date.issued | 2018-04-18 | |
dc.identifier.uri | http://repository.limu.edu.ly/handle/123456789/746 | |
dc.description | Recurrent aphthous stomatitis (RAS) remains the most common ulcerative disease of the oral
mucosa presenting as painful round shallow ulcers with well-defined erythematous margin
and yellowish-gray pseudomembranous center. RAS has a characteristic prodromal burning
sensation that lasts from 2 to 48 hours before an ulcer appears. It occurs in otherwise healthy
individuals and is typically located on the buccal and labial mucosa and tongue. Involvement
of the heavily keratinized mucosa of the palate and gingiva is less common.
Several factors have been proposed as possible causative agents for RAS. These include local
factors, such as trauma in individuals who are genetically susceptible to RAS, microbial
factors, nutritional factors, such as deficiency of folate and B-complex vitamins, immunologic
factors, psychosocial stress, and allergy to dietary constituents1
. Extensive research has
focused predominantly on immunologic factors, but a definitive etiology of RAS has yet to
be clearly established | en_US |
dc.description.abstract | Recurrent Aphthous Stomatitis (RAS) is the most common ulcerative disease affecting the
oral mucosa. It occurs mostly in healthy individuals and has atypical clinical presentation
in immunocompromised individuals. The etiology of RAS is still unknown, but several
local, systemic, immunologic, genetic, allergic, nutritional, and microbial factors, as well as
immunosuppressive drugs, have been proposed as causative agents. This review article
summarizes the clinical presentation and predisposing factor of recurrent aphthous
stomatitis. | en_US |
dc.language.iso | en | en_US |
dc.publisher | faculty of Basic Medical Science - Libyan International Medical University | en_US |
dc.rights | Attribution 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
dc.title | Clinical presentation and predisposing factor of recurrent aphthous stomatitis | en_US |
dc.type | Other | en_US |