How is Active Osteoarthritis Differ than Sero-negative Rheumatoid Arthritis in Clinical Diagnose ?

Abstract

Arthritis comes in many forms. In fact, this term can apply to a number of conditions, including, rheumatoid arthritis, gout, and osteoarthritis. Two of these conditions–rheumatoid arthritis (RA) and osteoarthritis (OA) are often confused among patients.1 OA is a degenerative condition that develops because of excessive wear to the cartilage between the joints. RA is an autoimmune disease, chronic systemic inflammatory disease that affects about 1% of the population. It leads to irreversible joint damage and systemic complications, Since the discovery by Waalcr and Rose et al. of the so-called rheumatoid factor, patients have been classified as seropositive or seroncgative. Twenty years ago, textbooks stated that one quarter of rheumatoid patients were seronegative, only 38% of patients are diagnosed with seronegative RA