Oncolytic Viruses for Cancer Immunotherapy

Ahmed, Ashraqat (2022-08-16)

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In preclinical and clinical research, oncolytic virotherapy has yielded promise but limited results. Induction of tumor-specific immunity is an important therapeutic mechanism of oncolytic virotherapy, in addition to direct oncolytic activity. As a result, the insertion of immune stimulator genes and sensible combinatorial therapy with other immunotherapies can boost the efficacy of oncolytic viruses.

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