dc.contributor.author | Mohamed Shein, Taima | |
dc.date.accessioned | 2020-09-30T07:25:26Z | |
dc.date.available | 2020-09-30T07:25:26Z | |
dc.date.issued | 2020-02-29 | |
dc.identifier.uri | http://repository.limu.edu.ly/handle/123456789/2054 | |
dc.description | Cancer is one of the most life treating multi-faceted diseases that occur on
account of uncontrolled cell production, accompanied by attack of local tissues
and their metastasize ability. Cancer is ranking third for leading death source
after infectious and cardiac diseases [1].
Two factors are involved which can caused cancer. These factors include
external factors such as, radiations, chemicals, tobacco, viruses etc. Internal
factors which involves, immune conditions, hormones and mutations (genetic
alterations give rise to changes in expression, activation or localization of
regulatory proteins in cells, affecting the signaling pathways that alter their
response to regulatory stimuli and allow the unrestricted cell growth). This may
act together or in sequence to instigate or promote carcinogenesis [1].
2
Ovarian cancer, the second most common gynecological cancer is still ranked
among the top 5 of female cancer deaths in the world. Because ovarian cancer is
often asymptomatic, the majority of patients with newly diagnosed ovarian
cancer present the disease in its advanced-stage. Ovarian cancer is a result
abnormal cells that have the ability to invade or spread to the other parts of the
body [1]. | en_US |
dc.description.abstract | Ovarian cancer, the second most common gynecological is still ranked among
the top 5 of female cancer death in word. The proliferation of tumor cell,
angiogenesis, and the relationship between the cancer cell and the component of
extracellular matrix and important in events of carcinogenesis, and these
pathways are being use as targets for new anticancer treatment. Various venoms
and their toxins have shown possible anticancer effect on ovarian cancer cell
line, providing new perspectives in drug development. In this report searcher
observed the effect of natural toxins from snake venom and mechanisms
through which they can inhibit the growth and proliferation of ovarian cancer
cell. This approach could improve the efficiency of normal therapies and could
allow the administration of decreased dose of chemotherapy natural toxins from
snake venom could become potential candidates for future treatment of ovarian
cancer. | en_US |
dc.language.iso | en | en_US |
dc.publisher | faculty of Basic Medical Science - Libyan International Medical University | en_US |
dc.rights | Attribution 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
dc.subject | snake venom; ovarian cancer; carcinogenesis; human epithelial cell lines | en_US |
dc.title | Effect of snake venom on ovarian cancer | en_US |
dc.type | Other | en_US |